MOPAC®

What MOPAC is

  MOPAC (Molecular Orbital PACkage) is a semiempirical quantum chemistry program based on Dewar and Thiel's NDDO approximation.
 
MOPAC2012   MOPAC2012 is MOPAC2009 plus the PM7 and PM7-TS methods.   It is currently in the beta test phase, and help in debugging is always appreciated.  If a bug is detected, please send a message by E-mail to MrMOPAC@OpenMOPAC.net, along with an example illustrating the bug. To avoid buggy executables spreading, the beta test executables will be limited to 100 days.  If you qualify for Academic not-for-profit use and already have a password for MOPAC 2009, go straight to download, otherwise request a password and download.

Commercial users in Europe and America, please contact CAChe Research (see Resellers)
Commercial users in Japan, please contact Ryoka Systems
Commercial users in Korea, please contact  KREIS I&C
 

PM7   PM7 is a modified form of PM6. A few errors in NDDO theory that affect large systems have been removed.  All atomic and diatomic parameters were re-optimized.  Average errors in organic compounds have been reduced by ~10%, and errors in large organics and solids have been significantly reduced, see PM7 Accuracy.
 
References
and Citations
  MOPAC2012   MOPAC2009PM6
Instructions and Manual   A manual is available for MOPAC2012.  Please try finding answers to questions there before sending an E-mail message requesting help.
 
Maintenance record     MOPAC2012 is under constant maintenance.  If your copy of MOPAC2012 does not work correctly, check the maintenance record to see if there is a more up-to-date version.
 

PM6

  PM6 is a re-parameterization of the NDDO method.  Three modifications to the approximations were made, these mainly affect the way the core-core interaction was defined.  Parameters were optimized for most elements, the exceptions being 12 of the lanthanides and all of the actinides.  The lanthanides can be represented by sparkles.  For details, see the on-line PM6 journal article, and its supplementary material.
 
Downloads  

Downloads of source and  binaries for the various older versions of MOPAC are available.
 

History   MOPAC was started in 1981, and has been under continuous development since then.
 
Older MOPAC Programs   MOPAC2009 is MOPAC2007 plus the MOZYME function.  MOZYME is a linear-scaling SCF method that allows systems of up to 15,000 atoms to be modeled.
MOPAC2007 was an improved version of MOPAC 7.1. In addition to the methods in MOPAC 7.1, it also included RM1 and PM6.
MOPAC 7.1 is a FORTRAN 90 version of MOPAC 7. It supports the methods: MNDO, AM1, and PM3, as well as Sparkle/AM1 for the lanthanides. All published NDDO parameter sets were supported. It is fully in the public domain. (Download source)
 
Availability   Windows, Linux, and Mac versions are supported.
 
Cooperative Development   The purpose of this site is to encourage cooperative development.  There is a default mechanism for contributing improvements.
 
Acknowledgment   This work was funded by the National Institute of General Medical Sciences (NIGMS), Grant No. 2 R44 GM067327-02
 
Example files   Ethane.xyz    co2.mop    plus(+)plus.html
 
Contacts   James Stewart, 15210 Paddington Circle, Colorado Springs, CO 80921
 E-mail : MrMOPAC@OpenMOPAC.net

SKYPE: Jimmy.Stewart2 (between 1500 and 2200 GMT)

The mark "MOPAC" is a trademark of James Stewart
Copyright 2007, Stewart Computational Chemistry.